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Drug Safety Update

From:: Medicines and Healthcare products Regulatory Agency

Alerts, recalls and safety information: medicines and medical devices

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115 updates

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115 updates

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115 updates

About Respiratory disease and allergy

Codeine-containing liquid over-the-counter medicines.

Should not be used for cough under 18 years
- Therapeutic area: Ear, nose and throat and 2 others
- Published: 11 December 2014
Long-acting 尾2-agonists: reminder for use in children and adults

Benefits of these medicines used in conjunction with inhaled corticosteroids (ICS) in the control of asthma symptoms in children outweigh any apparent risks.
- Therapeutic area: Respiratory disease and allergy
- Published: 11 December 2014
Inhaled and intranasal corticosteroids

Risk of psychological and behavioural side effects.
- Therapeutic area: Ear, nose and throat and 1 others
- Published: 11 December 2014
Modafinil: restricted use recommended

European Medicines Agency has recommends the use of modafinil should be restricted to treat only sleepiness associated with narcolepsy - should no longer be used for obstructive sleep apnoea or chronic shift work sleep disor鈥�
- Therapeutic area: Neurology and 1 others
- Published: 11 December 2014
Orciprenaline sulphate (Alupent): reminder of withdrawal from the market

Patients should be transferred to alternative bronchodilator therapy.
- Therapeutic area: Respiratory disease and allergy
- Published: 11 December 2014
Nicotine replacement therapy and harm reduction

Extension of the indication for nicotine replacement therapy (NRT) to include harm reduction.
- Therapeutic area: Cardiovascular disease and lipidology and 1 others
- Published: 11 December 2014
Orciprenaline sulphate (Alupent): withdrawal due to unfavourable benefit-risk profile

Patients who require a liquid oral formulation of a 尾-agonist should be switched to a more-selective short-acting 尾2-agonist such as salbutamol or terbutaline.
- Therapeutic area: Respiratory disease and allergy
- Published: 11 December 2014
Pseudoephedrine and ephedrine: nasal decongestants

How to reduce risk of illicit use.
- Therapeutic area: Ear, nose and throat and 1 others
- Published: 11 December 2014
Long-acting 尾-agonists: use in chronic obstructive pulmonary disease

Overall benefits of long-acting 尾-agonists (LABAs) in the treatment of chronic obstructive pulmonary disease (COPD) continue to outweigh any risks.
- Therapeutic area: Respiratory disease and allergy
- Published: 11 December 2014
Over-the-counter cough and cold medicines for children

Advice on how to use cough and cold medicines safely for children under 12 years.
- Therapeutic area: Paediatrics and neonatology and 1 others
- Published: 11 December 2014
Inhaled medicines containing corticosteroid

Licensed doses and differences in potency between different inhaled corticosteroids; advice for use with spacer device.
- Therapeutic area: Respiratory disease and allergy
- Published: 11 December 2014
Review on long-acting 尾2 agonists for asthma

Long-acting 尾2 agonists (LABA) should only be prescribed in conjunction with inhaled corticosteroids for the treatment of moderate to severe asthma.
- Therapeutic area: Respiratory disease and allergy
- Published: 11 December 2014
Talc for pleurodesis: adverse effects

We have recently advised that talc preparations for pleurodesis are to be considered as medicinal products.
- Therapeutic area: Respiratory disease and allergy
- Published: 11 December 2014
Ecoflac infusion solutions: risk of air embolism

To avoid the risk of air embolism, these products should not be infused under pressure.
- Therapeutic area: Anaesthesia and intensive care and 22 others
- Published: 11 December 2014
Inhaled corticosteroids: pneumonia

Physicians should remain vigilant for pneumonia and other infections of the lower respiratory tract (ie, bronchitis) in patients with chronic obstructive pulmonary disease who are treated with inhaled products that contain s鈥�
- Therapeutic area: Respiratory disease and allergy
- Published: 11 December 2014

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