Research and analysis
NOIDs causative agents: week 30 (week ending 30 July 2023)
Updated 2 January 2024
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Laboratories in England have a statutory duty to notify the UK Health Security Agency (UKHSA) of the identification of the following causative agents:
- Bacillus anthracis
- Bacillus cereus
- Bordetella pertussis
- Borrelia spp
- Brucella spp
- Burkholderia mallei
- Burkholderia pseudomallei
- Campylobacter spp
- Carbapenemase-producing Gram-negative bacteria
- Chikungunya virus
- Chlamydophila psittaci
- Clostridium botulinum
- Clostridium perfringens
- Clostridium tetani
- Corynebacterium diphtheriae
- Corynebacterium ulcerans
- Coxiella burnetii
- Crimean-Congo haemorrhagic fever virus
- Cryptosporidium spp
- Dengue virus
- Ebola virus
- Entamoeba histolytica
- Escherichia coli O 157
- Francisella tularensis
- Giardia lamblia
- Guanarito virus
- Haemophilus influenzae (invasive)
- Hanta virus
- Hepatitis A
- Hepatitis B
- Hepatitis C
- Hepatitis D
- Hepatitis E
- Influenza virus
- Junin virus
- Kyasanur Forest disease virus
- Lassa virus
- Legionella spp
- Leptospira interrogans
- Listeria monocytogenes
- Machupo virus
- Marburg virus
- Measles virus
- Mpox (monkeypox) virus
- Mumps virus
- Mycobacterium tuberculosis complex
- Neisseria meningitidis
- Omsk haemorrhagic fever virus
- Plasmodium falciparum
- Plasmodium knowlesi
- Plasmodium malariae
- Plasmodium ovale
- Plasmodium vivax
- Polio virus
- Rabies virus
- Rickettsia spp
- Rift Valley fever virus
- Rubella virus
- Sabia virus
- Salmonella spp
- SARS coronavirus
- Shigella spp
- Streptococcus group A (invasive)
- Streptococcus pneumoniae (invasive)
- Varicella zoster virus
- Variola virus
- Vibrio cholerae
- West Nile virus
- Yellow fever virus
- Yersinia pestis
Statutory notifications of causative agents, grouped by root organism
Totals for the current week compared to the previous 5.
| Week notification received | 2023/25 | 2023/26 | 2023/27 | 2023/28 | 2023/29 | 2023/30 |
|---|---|---|---|---|---|---|
| Arboviruses | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| West Nile virus | - | 1 | - | - | - | - |
| Bacillus | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Bacillus cereus | 24 | 19 | 29 | 35 | 27 | 14 |
| Bordetella | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Bordetella pertussis | 22 | 4 | 5 | 9 | 19 | 10 |
| Borrelia | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Borrelia burgdorferi | 22 | 28 | 28 | 29 | 38 | 37 |
| Borrelia sp | 4 | 4 | 6 | 6 | 2 | 3 |
| Borrelia tillae | - | 2 | 1 | 1 | 1 | - |
| Campylobacter | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Campylobacter coli | 70 | 47 | 41 | 46 | 46 | 25 |
| Campylobacter fetus | 1 | - | - | - | - | - |
| Campylobacter jejuni | 459 | 335 | 335 | 362 | 298 | 239 |
| Campylobacter lari | 1 | - | 1 | 1 | 2 | 1 |
| Campylobacter other named | 3 | 1 | 1 | - | - | 2 |
| Campylobacter sp | 1,333 | 1,415 | 1,332 | 1,248 | 1,100 | 1,115 |
| Campylobacter upsaliensis | 1 | 1 | 1 | 1 | - | 2 |
| Campylobacter ureolyticus (bacteroides corrodens) | 1 | - | 1 | - | 1 | - |
| Chikungunya virus | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Chikungunya virus | 1 | 2 | - | 4 | 3 | - |
| Clostridium | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Clostridium perfringens | 31 | 53 | 43 | 24 | 24 | 27 |
| Coronavirus | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Coronavirus | 21 | 8 | 14 | 4 | 7 | 10 |
| SARS-CoV-2 antibody indeterminate | 109 | 60 | 88 | 61 | 69 | 124 |
| SARS-CoV-2 antibody void | 4 | 4 | 4 | 2 | 4 | 6 |
| SARS-CoV-2 coronavirus (COVID-19) | 2,504 | 1,871 | 2,255 | 2,795 | 3,224 | 4,236 |
| SARS-CoV-2 coronavirus (COVID-19) indeterminate | 28 | 28 | 34 | 24 | 21 | 24 |
| SARS-CoV-2 IgG antibody negative | 75 | 50 | 46 | 56 | 53 | 56 |
| SARS-CoV-2 IgG antibody positive | 346 | 127 | 132 | 144 | 169 | 151 |
| SARS-CoV-2 total antibody negative | 42 | 24 | 44 | 60 | 65 | 38 |
| SARS-CoV-2 total antibody positive | 125 | 126 | 117 | 155 | 125 | 89 |
| Corynebacterium | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Corynebacterium diphtheriae | 3 | - | 4 | 1 | 1 | 4 |
| Corynebacterium ulcerans | - | - | 2 | 1 | - | - |
| Cryptosporidium | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Cryptosporidium cuniculus | - | - | - | 1 | - | - |
| Cryptosporidium felis | - | 1 | - | 1 | - | - |
| Cryptosporidium hominis | 5 | 8 | 13 | 18 | 6 | 9 |
| Cryptosporidium meleagridis | 1 | - | 1 | 1 | - | 1 |
| Cryptosporidium parvum | 43 | 33 | 23 | 30 | 12 | 11 |
| Cryptosporidium sp | 22 | 9 | 31 | 30 | 27 | 56 |
| Entamoeba | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Entamoeba histolytica | 1 | 1 | 2 | 2 | - | 1 |
| Escherichia | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Escherichia coli O 157 | 20 | 18 | 20 | 16 | 11 | 14 |
| Flaviviruses | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Dengue virus | 1 | 4 | 2 | 5 | 1 | 3 |
| Haemophilus | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Haemophilus influenzae | 65 | 74 | 66 | 60 | 42 | 56 |
| Hepatitis viruses | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Hepatitis A | 16 | 10 | 13 | 10 | 4 | 8 |
| Hepatitis B | 303 | 331 | 235 | 293 | 287 | 240 |
| Hepatitis C | 447 | 431 | 443 | 360 | 377 | 309 |
| Hepatitis D | 8 | 7 | 5 | 4 | 5 | 5 |
| Hepatitis E | 29 | 47 | 36 | 32 | 38 | 26 |
| Influenza virus | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Influenza A | 60 | 25 | 57 | 59 | 52 | 56 |
| Influenza B | 26 | 15 | 15 | 22 | 16 | 16 |
| Influenza indeterminate | 1 | - | - | 52 | - | - |
| Influenza ungrouped | 2 | 1 | - | 1 | 1 | - |
| Legionella | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Legionella longbeachae | - | - | 1 | - | 3 | - |
| Legionella pneumophila | 10 | 10 | 6 | 8 | 13 | 14 |
| Legionella sp | 2 | 3 | 3 | 4 | 8 | 11 |
| Listeria | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Listeria monocytogenes | 16 | 5 | 8 | 3 | 4 | 1 |
| Mycobacterium | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Mycobacterium tuberculosis | 103 | 89 | 96 | 76 | 65 | 66 |
| Neisseria | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Neisseria meningitidis | 19 | 12 | 20 | 16 | 16 | 19 |
| Orthopoxvirus | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Mpox virus | 4 | 1 | 3 | 3 | 2 | 3 |
| Paramyxoviruses | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Measles virus | 6 | 7 | 3 | 4 | 10 | 4 |
| Mumps virus | 2 | 2 | 6 | 5 | 3 | 4 |
| Plasmodium | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Plasmodium falciparum | 1 | 12 | 4 | 2 | - | 1 |
| Plasmodium malariae | - | 1 | - | - | - | - |
| Plasmodium ovale | - | 1 | - | - | - | - |
| Polyomavirus | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Polyomavirus BK | 86 | 46 | 41 | 40 | 48 | 40 |
| Polyomavirus JC | 13 | 11 | 19 | 9 | 9 | 9 |
| Polyomavirus untyped | 2 | 1 | 1 | - | - | 1 |
| Rickettsia | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Rickettsia mooseri | - | - | - | - | 1 | - |
| Rickettsia spotted fever | - | 1 | - | - | - | - |
| Rubella virus | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Rubella virus | 5 | 2 | 1 | 2 | 1 | 3 |
| Salmonella | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Other salmonellas | 65 | 74 | 54 | 49 | 29 | 23 |
| Salmonella agona | - | - | 5 | - | - | - |
| Salmonella chester | 6 | - | - | - | - | - |
| Salmonella enteritidis | 85 | 96 | 61 | 50 | 19 | - |
| Salmonella infantis | - | 8 | 7 | - | 6 | - |
| Salmonella kentucky | - | 5 | - | - | - | - |
| Salmonella newport | - | - | 6 | - | - | - |
| Salmonella sp | 23 | 22 | 26 | 93 | 133 | 150 |
| Salmonella typhi and paratyphi | 9 | 10 | 7 | 13 | 9 | - |
| Salmonella typhimurium | 33 | 30 | 34 | 32 | 19 | - |
| Salmonella virchow | - | 5 | - | - | - | - |
| Shigella | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Shigella boydii | - | 2 | - | - | 1 | - |
| Shigella dysenteriae | 1 | 1 | - | - | 1 | 1 |
| Shigella flexneri | 6 | 10 | 11 | 9 | 6 | 3 |
| Shigella sonnei | 24 | 32 | 20 | 20 | 20 | 19 |
| Shigella sp | 49 | 52 | 50 | 48 | 33 | 61 |
| Streptococcus | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Streptococcus group A | 91 | 65 | 56 | 69 | 63 | 53 |
| Streptococcus pneumoniae | 106 | 69 | 70 | 65 | 54 | 57 |
| Vibrio | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Vibrio cholerae | - | - | - | 1 | 1 | 2 |
Carbapenemase-producing Enterobacterales (CPE)
For all Carbapenemase-producing Gram-negative organisms, the reports are de-duplicated by first mention of organism species and resistance mechanism by person in a rolling 52-week period.
Note: the numbers presented here do not include specimens that have been referred to the AMRHAI Reference Unit.
| Week notification received | 2023/25 | 2023/26 | 2023/27 | 2023/28 | 2023/29 | 2023/30 | |
|---|---|---|---|---|---|---|---|
| Citrobacter | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Citrobacter spp | KPC | - | - | 1 | 2 | 2 | - |
| Ìý | NDM | 1 | 1 | 1 | 1 | - | - |
| Ìý | OXA48 | 1 | 1 | 1 | 2 | 2 | 3 |
| Ìý | VIM | - | - | 1 | - | - | - |
| Ìý | Other | - | - | 4 | 2 | 3 | - |
| Cronobacter | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Cronobacter malonaticus | NDM | - | 1 | - | - | - | - |
| Enterobacter | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Enterobacter cloacae complex | IMP | 3 | 3 | 4 | - | - | - |
| Ìý | KPC | 2 | 1 | 2 | 2 | 10 | 5 |
| Ìý | NDM | 7 | 6 | 2 | - | 4 | - |
| Ìý | OXA48 | 2 | 7 | 2 | 2 | 1 | 1 |
| Ìý | VIM | - | - | 1 | - | 1 | - |
| Ìý | Other | 1 | 4 | 2 | 4 | 2 | - |
| Other enterobacter spp | KPC | - | 1 | - | 1 | - | - |
| Ìý | NDM | 1 | 1 | - | 1 | - | - |
| Ìý | OXA48 | - | 1 | - | 2 | - | - |
| Ìý | VIM | 1 | - | - | - | - | - |
| Escherichia | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Escherichia coli | KPC | 8 | 2 | 4 | 3 | 7 | 7 |
| Ìý | NDM | 14 | 9 | 16 | 12 | 18 | 6 |
| Ìý | OXA48 | 12 | 12 | 9 | 4 | 12 | 3 |
| Ìý | VIM | 1 | 1 | - | - | - | - |
| Ìý | Other | 1 | 2 | 1 | 1 | 2 | 1 |
| Klebsiella | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Klebsiella aerogenes | KPC | - | 1 | - | - | - | 1 |
| Ìý | Other | - | 1 | 1 | 2 | - | - |
| Klebsiella oxytoca | KPC | - | 1 | - | 1 | 2 | 3 |
| Ìý | NDM | - | 1 | - | - | - | 1 |
| Ìý | OXA48 | 1 | - | - | 1 | 1 | 1 |
| Ìý | VIM | - | - | 1 | - | - | - |
| Ìý | Other | 1 | - | - | - | - | - |
| Klebsiella pneumoniae | KPC | 8 | 10 | 13 | 5 | 6 | 4 |
| Ìý | NDM | 8 | 5 | 8 | 8 | 6 | 2 |
| Ìý | OXA48 | 7 | 11 | 5 | 10 | 7 | 2 |
| Ìý | VIM | 1 | - | - | 1 | 1 | - |
| Ìý | Other | 1 | 1 | 1 | 1 | 2 | - |
| Klebsiella pneumoniae subsp ozenae | NDM | - | - | 1 | - | - | - |
| Ìý | Other | - | - | 1 | - | - | - |
| Klebsiella serogenes | NDM | 1 | - | - | - | - | - |
| Ìý | OXA48 | 1 | - | - | - | - | - |
| Ìý | VIM | 1 | - | - | - | - | - |
| Ìý | Other | 1 | - | - | - | - | - |
| Klebsiella variicola | NDM | - | - | - | 1 | - | - |
| Ìý | OXA48 | - | - | - | - | 1 | - |
| Other klebsiella spp | OXA48 | 1 | - | - | - | - | - |
| Morganella | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Morganella morganii | Other | - | - | 2 | 4 | 1 | - |
| Pantoea | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Pantoea agglomerans | KPC | - | - | - | 1 | - | - |
| Pluralibacter | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Pluralibacter gergoviae | Other | 1 | - | - | - | - | - |
| Proteus | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Proteus mirabilis | NDM | - | - | - | - | - | 1 |
| Serratia | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Serratia marcescens/ureilytica | Other | - | - | 2 | - | - | - |
Other carbapenemase-producing Gram-negative organisms
For all Carbapenemase-producing Gram-negative organisms, the reports are de-duplicated by first mention of organism species and resistance mechanism by person in a rolling 52-week period.
Note: the numbers presented here do not include specimens that have been referred to the AMRHAI Reference Unit.
| Week notification received | 2023/25 | 2023/26 | 2023/27 | 2023/28 | 2023/29 | 2023/30 | |
|---|---|---|---|---|---|---|---|
| Acinetobacter | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Acinetobacter baumannii | IMP | 1 | - | - | - | - | - |
| Ìý | NDM | - | - | - | - | - | 1 |
| Acinetobacter calcoaceticus/baumannii complex | IMP | 1 | - | - | - | - | - |
| Acinetobacter pittii | NDM | - | 1 | - | - | - | - |
| Other acinetobacter spp | NDM | 1 | - | - | - | - | - |
| Pseudomonas | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Pseudomonas aeruginosa | IMP | - | 1 | - | - | - | - |
| Ìý | NDM | - | 1 | 1 | - | - | 2 |
| Ìý | VIM | 1 | - | 1 | 1 | - | 1 |
| Ìý | Other | 1 | 2 | 1 | 1 | 3 | 2 |
| Pseudomonas nitroreducens | VIM | - | - | - | - | - | 1 |
| Other | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý | Ìý |
| Ìý | Other | - | - | 1 | 1 | - | - |