Guidance
Complete routine immunisation schedule from 1 July 2025
Updated 3 June 2025
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Routine immunisation programmes
| Age due | Vaccines that protect against | Vaccine given | Trade name | Usual site听[note 1] | |
|---|---|---|---|---|---|
| 8 weeks old | Diphtheria, tetanus, pertussis (whooping cough), polio, Haemophilus influenzae type b (Hib) and hepatitis B | DTaP/IPV/Hib/HepB听(6 in 1 vaccine) | Infanrix hexa or Vaxelis | Thigh | 听 |
| 听 | Meningococcal group B (MenB) | MenB | Bexsero | Thigh | 听 |
| 听 | Rotavirus gastroenteritis | Rotavirus | Rotarix听[note 2] | By mouth | 听 |
| 12 weeks old | Diphtheria, tetanus, pertussis (whooping cough), polio, Haemophilus influenzae type b (Hib) and hepatitis B | 听 | DTaP/IPV/Hib/HepB听(6 in 1 vaccine) | Infanrix hexa or Vaxelis | Thigh |
| 听 | MenB | MenB | Bexsero | Thigh | 听 |
| 听 | Rotavirus | Rotavirus | Rotarix听[note 2] | By mouth | 听 |
| 16 weeks old | Diphtheria, tetanus, pertussis (whooping cough), polio, Haemophilus influenzae type b (Hib) and hepatitis B | DTaP/IPV/Hib/HepB听(6 in 1 vaccine) | Infanrix hexa or Vaxelis | Thigh | 听 |
| 听 | Pneumococcal (13 serotypes) 鈥� if received pneumococcal at 12 weeks give Men B |
听 | PCV | Prevenar 13 | Thigh |
| One year old (on or after the child鈥檚 first birthday) | Born before 1 July 2024 | Born on or after 1 July 2024 | |||
|---|---|---|---|---|---|
| 听 | Pneumococcal | Pneumococcal | PCV | Prevenar 13 | Upper arm or thigh |
| 听 | Measles, mumps, rubella | Measles, mumps, rubella | MMR | MMRvaxPro or Priorix | 听 |
| 听 | MenB | MenB | MenB | Bexsero | 听 |
| 听 | Hib/MenC听(if听Hib/MenC听exhausted give DTaP/Hib/IPV/HepB) | 听 | Hib/MenC | Menitorix | 听 |
| 18 months old | Born before 1 July 2024 | Born on or after 1 July 2024 | |||
|---|---|---|---|---|---|
| 听 | No appointment | DTaP/IPV/Hib/HepB | DTaP/IPV/Hib/HepB | Infanrix hexa or Vaxelis | Upper arm or thigh |
| 听 | 听 | Measles, mumps, rubella | MMR | MMRvaxPro or Priorix | 听 |
| 3 years 4 months old or soon after | Born before 1 July 2024 | Born on or after 1 July 2024 | 听 | 听 | 听 |
| 听 | Diphtheria, tetanus, pertussis and polio | Diphtheria, tetanus, pertussis and polio | dTaP/IPV | REPEVAX | Upper arm or thigh |
| 听 | Measles, mumps, rubella | 听 | MMR | MMRvaxPro or Priorix | 听 |
| Age due | Vaccines that protect against | Vaccine given | Trade name | Usual site听[footnote 1] |
|---|---|---|---|---|
| Boys and girls aged 12 to 13 years | Cancers and genital warts caused by specific human papillomavirus (HPV) types | HPV | Gardasil 9 | Upper arm |
| 14 years old (school Year 9) | Tetanus, diphtheria and polio | Td/IPV | REVAXIS | Upper arm |
| 听 | Meningococcal groups A, C, W and Y | MenACWY | MenQuadfi | Upper arm |
| Eligible paediatric age group See听annual flu letter (each year from September) |
Influenza |
LAIV听(Live attenuated influenza vaccine) 鈥� If听LAIV听is contraindicated or otherwise unsuitable use inactivated flu vaccine (check听Green Book chapter 19听for details) |
Fluenz (contains porcine gelatine) | Both nostrils |
| 65 years old | Pneumococcal (23 serotypes) | Pneumococcal polysaccharide vaccine (PPV23) | Pneumovax 23 | Upper arm |
| 65 years of age and older | Influenza (each year from September) | Inactivated influenza vaccine | Multiple | Upper arm |
| 65 from September 2023听) | Shingles | Shingles vaccine | Shingrix | Upper arm |
| 70 to 79 years of age (plus eligible age groups and severely immunosuppressed) | Shingles | Shingles vaccine | Zostavax听 (or Shingrix if Zostavax contraindicated) |
Upper arm |
| 75 years old | Respiratory syncytial virus (RSV) | RSV听vaccine | Abrysvo | Upper arm |
Notes
- Intramuscular injection into deltoid muscle in upper arm or anterolateral aspect of the thigh.
- Rotavirus vaccine should only be given after checking for SCID screening result.
Selective immunisation programmes
| Target group | Age and schedule | Disease | Vaccines required | |
|---|---|---|---|---|
| Babies born to women with hepatitis B infection 听[note 1],听[note 2 | At birth, 4 weeks if born before 01 July 2024 give additional dose at 12 months old听[note 1] |
Hepatitis B | Hepatitis B (Engerix B/HBvaxPRO) | 听 |
| Infants in areas of the country with tuberculosis (TB) incidence >= 40/100,000 | Around 28 days old听[note 4] | Tuberculosis | BCG | 听 |
| Infants with a parent or grandparent born in a high incidence country听[note3] | Around 28 days old听[note 4] | Tuberculosis | BCG | 听 |
| Children in a clinical risk group | Age under 2 years 鈥� if first ever flu vaccine give second dose at 4 weeks |
Influenza | inactivated flu vaccine | 听 |
| 听 | Age under 2 years 鈥� if first ever flu vaccine give second dose at 4 weeks |
Influenza | LAIV听or inactivated flu vaccine if contraindicated to听LAIV听 | 听 |
| 听 | Age 9 to 17 years 鈥� one dose required each flu season |
Influenza | LAIV听or inactivated flu vaccine if contraindicated to听LAIV听 | 听 |
| Pregnant women | At any stage of pregnancy during flu season | Influenza | Inactivated flu vaccine | 听 |
| 听 | From 16 weeks gestation听[note 5] | Pertussis | Tdap听(ADACEL) | 听 |
| 听 | From 28 weeks gestation | RSV | RSV听vaccine (Abrysvo) | 听 |
Notes
- Take blood for HBsAg on or after 12 months to exclude infection. For children born on or after 1 July 2024, test anytime between 12 and 18 months.
- In addition hexavalent vaccine (Infanrix hexa or Vaxelis) is given at 8, 12 and 16 weeks and, for children born on or after 1 July 2024, also at 18 months.
- Where the annual incidence of TB is 40 per 100,000 or higher 鈥� see TB incidence by country.
- Check SCID screening outcome before giving BCG.
- Ideally before 32 weeks gestation but may still be given after 32 weeks.
Additional vaccines for individuals with underlying medical conditions
| Medical condition | Diseases protected against | Vaccines required听[note 1] |
|---|---|---|
| Asplenia or splenic dysfunction听 (this also includes individuals with coeliac disease who are diagnosed with splenic dysfunction and all haemoglobinopathies including homozygous sickle cell disease) |
Meningococcal groups A, B, C, W and Y |
MenACWY MenB |
| 听 | Pneumococcal |
PCV13听(up to 10 years of age)听[note 2] PPV23 (from 2 years of age) |
| 听 | Influenza | Annual flu vaccine |
| Cochlear implants | Pneumococcal |
PCV13听(up to 10 years of age)听[note 2] PPV23 (from 2 years of age) |
| Chronic respiratory and heart conditions听(such as severe asthma, chronic pulmonary disease, and heart failure) | Pneumococcal |
PCV13听(up to 10 years of age)[note 2] PPV23 (from 2 years of age) |
| 听 | Influenza | Annual flu vaccine |
| Chronic neurological conditions | Pneumococcal (only if the individual is also at increased risk of aspiration) |
PCV13听(up to 10 years of age)听[note 2] PPV23 (from 2 years of age) |
| 听 | Influenza | Annual flu vaccine |
| Diabetes | Pneumococcal |
PCV13听(up to 10 years of age)听[note 2] PPV23 (from 2 years of age) |
| 听 | Influenza | Annual flu vaccine |
| Chronic kidney disease (CKD)听(including haemodialysis) | Pneumococcal (stage 4 and 5听CKD) |
PCV13听(up to 10 years of age)听[note 2] PPV23 (from 2 years of age) |
| 听 | Influenza (stage 3, 4 and 5听CKD) | Annual flu vaccine |
| 听 | Hepatitis B (stage 4 and 5听CKD) | Hepatitis B |
| Chronic liver conditions | Pneumococcal |
PCV13听(up to 10 years of age)听[note 2] PPV23 (from 2 years of age) |
| 听 | Influenza | Annual flu vaccine |
| 听 | Hepatitis A | Hepatitis A |
| 听 | Hepatitis B | Hepatitis B |
| Haemophilia | Hepatitis A | Hepatitis A |
| 听 | Hepatitis B | Hepatitis B |
| Immunosuppression听due to disease or treatment听[note 4] | Pneumococcal |
PCV13听(up to 10 years of age)听[note 2] ,[note 3] PPV23 (from 2 years of age) |
| 听 | Shingles vaccine | Shingrix 鈥� over 50 years of age听[note 5] |
| 听 | Influenza | Annual flu vaccine |
| Complement disorders听(including those receiving complement inhibitor therapy) | Meningococcal groups A, B, C, W and Y |
MenACWY MenB |
| 听 | Pneumococcal |
PCV13听(up to 10 years of age)听[note 2] PPV23 (from 2 years of age |
| 听 | Influenza | Annual flu vaccine |
Notes
- Check relevant chapter of the Green Book for specific schedule.
- If aged 2 years to under 10 years of age and unimmunised or partially immunised against pneumococcal infection, give one PCV13 dose.
- To any age in severely immunosuppressed.
- Consider annual influenza vaccination for household members and those who care for people with these conditions.
- Check Green Book Shingles Chapter 28a www.gov.uk/government/publications/ shingles-herpes-zoster-the-green-book-chapter-28a